Idarucizumab can also be used prophylactically in patients taking dabigatran who need emergency surgery or other urgent procedures. What is the antidote for dabigatran?Ī new direct antidote to treat life-threatening or uncontrolled bleeding related to dabigatran use, idarucizumab (Praxbind), has been approved by the Food and Drug Administration (FDA). This medicine is to be given only by or under the supervision of your doctor or other health care professional. The median hospital reimbursement was $11,492/hospitalization.Ĭoagulation factor Xa (recombinant), inactivated-zhzo injection is used to treat life-threatening or uncontrolled bleeding in patients who are receiving other medicines (including apixaban and rivaroxaban). The median projected cost of andexanet was $22,120/patient, compared to $5670/patient for 4F-PCC (P < 0.001).

To reduce the total reconstitution time needed during preparation, reconstitute all required vials in succession.

Slowly inject the SWFI, directing the solution onto the inside wall of the vial to minimize foaming.

Use a a 20-mL (or larger) syringe and 20-gauge (or higher) needle.

Cost of andexxa